Designed by Guiseppe Perugini with Uga de Plaisant and Raynaldo Perugini, Casa Sperimentale was built on a large, well-treed corner plot in an area of villas within the pine forest at Fregene, Italy.

The house was constructed between 1968 and 1975 as an experimental villa for weekend occupation. Fregene, a coastal resort about 30 km from Rome, became culturally prominent in the 1960s and 1970s when it was at the centre of the worlds of cinema and fashion.